ANÁLISE DO ÂNGULO DE FASE COMO PREDITOR PROGNÓSTICO EM PACIENTES COM CÂNCER DE MAMA

Abstract

This study followed the Cochrane Institute's guidelines for a narrative review, using the PICO method to select scientific articles from the National Library of Medicine search platform. The study identifies a prognostic phase angle (PA) cut-off point of 5.6º for breast neoplasia. Further studies are proposed to investigate and utilize PA cut-off points as prognostic factors for better clinical management. The phase angle (PA) is a parameter generated by bioelectrical impedance analysis, which reflects cellular integrity and hydration status, serving as a promising indicator of mortality in oncology patients. Therefore, it is crucial to establish clear cutoff points for clinical guidance, given the variability in PA values according to each patient's individuality. Thus, the aim of this narrative review was to evaluate PA as a prognostic predictor in breast cancer patients and survivors and to identify cutoff points used in different studies. Original scientific articles were searched in the MEDLINE/PUBMED database, and after applying established criteria, 11 articles were included for analysis. It was identified that the most commonly used cutoff point for prognostic evaluations is 5.6°, influenced by patient intrinsic variables such as the presence of lymphedema, BMI, and gender. The need for further studies to better characterize this important parameter and its clinical applicability was observed.